Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia
Papillomaviruses have evolved over many millions of years to propagate themselves at specific epithelial niches in a range of different host species.This has led to the great diversity of papillomaviruses that now exist, and to the appearance of distinct strategies for epithelial persistence.Many papillomaviruses minimise the risk of immune clearan